Expression of miR-34a in rat hearts with cardiac fibrosis and its effects on cardiac fibrosis

A: miR-34a expression levels in rat hearts from the Control group and ISO group. B: AAV vector schematic for miR-34a inhibition. C: AAV vector schematic for MTUS1 knockdown. D: Representative fluorescence images of left ventricular myocardium from different treatment groups (×10; scale bar = 100 μm). E: quantitative analysis of fluorescence intensity in myocardial tissues from different groups. AAV-NC: adeno-associated virus - negative control; ISO: isoproterenol. Data are presented as mean ± SD; n = 4 per group. *P < 0.05, #P < 0.005.