N-Terphenylpicolinamide derivatives designed to target PD-L1 increase activation and proliferation of T cells, and their cytotoxic properties toward cancer cells - research data

Repozytorium Otwartych Danych Badawczych Uczelni Krakowskich - Uniwersytet Jagielloński 2026 Dataset Open access

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Authors: Damian Muszak, Justyna Kocik-Krol, Julia Ząber, Oskar Kruc, Urszula Palej, Karolina Fijolkowska, Agnieszka Maslanka, Katarzyna Magiera‐Mularz, Jacek Plewka, Małgorzata Stec, Marcin Surmiak, Małgorzata Szafarz
+6 more Maciej Siedlar, Bogdan Musielak, Radosław Kitel, Elżbieta Wyska, Łukasz Skalniak, Ewa Surmiak
DOI: 10.57903/uj/h4ouev
Cited by: 0

Abstract

Raw experimental dataset for the publication "N-Terphenylpicolinamide derivatives designed to target PD-L1 increase activation and proliferation of T cells, and their cytotoxic properties toward cancer cells" (https://doi.org/10.1016/j.ejmech.2026.118652) consist of the inhibitors characerisation (1H,13C NMR, IR, UPLC/MS, HRMS), PD-1/PD-L1 ICB assay, TSA assay, LDPA assay, pharmacocinetics studies and NMR studies, molecular docking and crystallography

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Synthesis and biological activity Synthesis and Characterization of Heterocyclic Compounds

Publication details

Journal / source
Repozytorium Otwartych Danych Badawczych Uczelni Krakowskich - Uniwersytet Jagielloński
Publication date
9 February 2026
Language
EN
Document type
Dataset