Gepotidacin (Blujepa) — A New Antibiotic for Uncomplicated UTI

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Abstract

The FDA has approved gepotidacin (Blujepa – GSK), a triazaacenaphthylene bacterial type II topoisomerase inhibitor, for oral treatment of uncomplicated urinary tract infections (uUTI) in female patients ≥12 years old who weigh ≥40 kg. Gepotidacin is the first triazaacenaphthylene antibiotic to be approved in the US.

Fields of Study & Subjects

Urinary Tract Infections Management Cancer therapeutics and mechanisms Bladder and Urothelial Cancer Treatments

Publication details

Journal / source
˜The œmedical letter on drugs and therapeutics/˜The œmedical letter
Volume
68
Issue
1745
Pages
1–3
Publication date
5 January 2026
Language
EN