In Brief: A New Indication for Uzedy

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Abstract

Uzedy, an extended-release, subcutaneous (SC) formulation of the second-generation antipsychotic drug risperidone, was approved by the FDA in 2023 for treatment of schizophrenia in adults. It has now been approved for use as monotherapy or in combination with lithium or valproate for maintenance treatment of bipolar I disorder in adults. Extended-release, intramuscular (IM) formulations of risperidone (Risperdal Consta and Rykindo) are also approved for treatment of bipolar I disorder (see Table 1).

Fields of Study & Subjects

Bipolar Disorder and Treatment Phosphodiesterase function and regulation Chemical Reactions and Isotopes

Publication details

Journal / source
˜The œmedical letter on drugs and therapeutics/˜The œmedical letter
Volume
68
Issue
1746
Pages
15–16
Publication date
19 January 2026
Language
EN