Maternal Anti-RSV IgG Titers and Severe Respiratory Syncytial Virus Disease in Infants with Congenital Heart Disease

Respiratory syncytial virus (RSV) is a very common virus that affects almost all children under 2 years of age, and 50% of children under 1 year have been infected twice [1]. Despite significant improvements in clinical treatment, infants and children with severe congenital heart disease has increased risk to developed respiratory failure and congestive heart failure because of RSV infection. The risk of these infants developing a nosocomial infection during RSV epidemics may not have decreased over the past 15 years [2]. Objective(s): To associate in infants prenatally diagnosed with significant congenital heart disease, the presence of severe RSV disease and its relationship with serum levels of maternal IgG anti-RSV antibodies quantified in the third month of gestation.