NOVEL VESICULAR DRUG DELIVERY SYSTEMS: LIPOSOMES, NIOSOMES AND TRANSFEROSOMES

Novel vesicular drug delivery systems (VDDS) represent a major advancement in pharmaceutical technology, offering effective solutions to the limitations associated with conventional dosage forms. These systems enhance drug solubility, stability, bioavailability, and therapeutic efficacy while reducing systemic toxicity and dosing frequency. Among various vesicular carriers, liposomes, niosomes, and transferosomes have gained considerable importance due to their structural versatility, biocompatibility, and adaptability for targeted, controlled, and transdermal drug delivery. This chapter provides a comprehensive discussion on vesicular drug delivery systems with special emphasis on liposomes, niosomes, and transferosomes, including their composition, methods of preparation, mechanisms of drug delivery, advantages, limitations, recent advances, and marketed formulations. The chapter also highlights their future potential in modern pharmaceutical development.