Two-Stage Knee Arthroplasty in Tuberculous and Non-Specific Gonitis

The objective: to evaluate the use of two-stage arthroplasty in the treatment of a destructive form of septic gonitis of tuberculous and non-specific etiology including HIV-positive patients . Subjects and Methods . 15 patients with a destructive form of septic gonitis of both non-specific and tuberculous etiology were enrolled in the study, all those patients underwent surgical treatment. In 7/15 (46.67%) patients, the disease was caused by M. tuberculosis, in 8 (53.33%) it was a non-specific disease, and 5/15 (33.33%) patients were HIV-positive. The patients were planned to undergo a two-stage endoprosthetics using cemented articulating spacers saturated with antimicrobial drugs, according to the drug susceptibility of the pathogen. 10 patients (66.67%) underwent a full cycle of two-stage endoprosthetics, and 5 cases (33.33%) underwent the first stage only. Results. In all 15 cases, sustained eradication of the infection was achieved. In 10 patients who completed the entire cycle of surgical treatment, a statistically significant improvement in the KSS scores was obtained from 35.4 ± 15.4 to 78.2 ± 15.1 (p