Syphilis screening and evaluation of urea, creatinine and transaminases in HIV-positive patients with or without antiretroviral treatment, in the commune of Adjam, Cte dIvoire

Syphilis is a common, preventable, and treatable sexually transmitted infection caused by a spirochete bacterium, Treponema pallidum, a subspecies of pallidum. There is a co-infection between Human Immunodeficiency Virus (HIV) and syphilis. The general objective of this study is to evaluate the seroprevalence of syphilis, the levels of urea, creatinine and transaminases in HIV-positive patients with or without antiretroviral treatment, followed in three HIV care centers in the commune of Adjamé, Côte d’Ivoire. The study population consisted of HIV-positive patients newly screened, without antiretroviral treatment and HIV-positive patients under antiretroviral treatment, all aged 15 and over. Sociodemographic characteristics were obtained from a survey form. Screening of syphilis was carried out with two immunological tests that are Treponema Pallidum Hemagglutination Test (TPHA) and Rapid Plasma Reagin (RPR) -Charcoal. There were 40 HIV-positive patients without antiretroviral treatment (HIV+) and 12 HIV-positive patients under antiretroviral treatment (HIV+/ART). Among all patients, only one pregnant woman under antiretroviral treatment had HIV/Syphilis co-infection, representing a seroprevalence of 1.82%. The Pregnant patient with co-infection HIV/Syphilis had a value of alanine aminotransferase of 47 UI/L higher than of normal values. Co-infection HIV/Syphilis still exists. The pregnant woman with HIV/Syphilis co-infection would have a beginning of distortion of hepatic function. Key words: Seroprevalence, HIV-syphilis co-infection, urea, creatinine, transaminases, Côte d’Ivoire.