Serum cystatin C as a biomarker in non-Hodgkin lymphoma and its relationship with paraoxonase 1 activity

Journal of Medical Biochemistry 2026 Open access

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Authors: Bosa Mirjanić-Azarić, Smiljana Mijić, Zana Radic Savic, Siniša Stanković, Dragana Malčić-Zanić, Egeljić Mihailović, Đorđe Stojisavljević, Bojana Ivetic, Nataša Bogavac‐Stanojević
DOI: 10.5937/jomb0-61502
Cited by: 0
References: 23

Abstract

Background: This pilot study aimed to assess the potential of cystatin C (Cys C) as a biomarker in non-Hodgkin lymphoma (NHL) and to explore its association with paraoxonase 1 (PON1) activity. Methods: The study included 44 patients with B-cell NHL and 44 healthy subjects. Cys C was measured using the Cobas e 801 analyser (Roche Diagnostics GmbH, Mannheim, Germany), while PON1 and TAS were measured on the ILab 300+ system (Instrumentation Laboratory, Milan, Italy). Results: The serum level of Cys C (mg/L) was significantly higher in NHL patients compared to control subjects: 1.03 (0.88-1.24) vs 0.83 (0.78-0.90), P

Fields of Study & Subjects

Lymphoma Diagnosis and Treatment Paraoxonase enzyme and polymorphisms Inflammatory Biomarkers in Disease Prognosis

Publication details

Journal / source
Journal of Medical Biochemistry
Volume
45
Issue
4
Pages
889–896
Publication date
1 January 2026
Language
EN