Correlation analysis of the serum LDH, b2-MG, IL-2R and IL-10 levels in lymphoma patients

Background: To investigate the variations and clinical relevance of blood levels of b2-microglobulin (b2-MG), interleukin (IL)-2R, IL-10, and lactate dehydrogenase (LDH) in patients with lymphoma who have various circumstances. Methods: A total of 200 lymphoma patients diagnosed in this hospital from 2021 to 2025 were selected as the lymphoma group. Serum samples and data on age, sex, lymphoma tissue type, immunological type, clinical stage, bone marrow infiltration, and Epstein-Barr virus (EBV) infection were collected. During the same period, serum samples and data from 80 healthy individuals who underwent physical examinations (the control group) were collected. The levels of serum LDH, b2-MG, IL-2R and IL-10. Changes in the levels of each index in lymphoma tissue, tissue immunological type, clinical stage, bone marrow infiltration, and Epstein-Barr virus (EBV) infection and after effective treatment were analysed. Results: The lymphoma group had greater levels of serum LDH, b2-MG, IL-2R, and IL-10 than the control group (P