The predictive value of serum PAF-AH and visinin-like protein 1 for poor prognosis in patients with hypertensive intracerebral hemorrhage

Background: To determine if serum levels of retinoid protein-like protein 1 (VILIP-1), Platelet-Activating Factor Acetylhydrolase (PAF-AH), and 8-hydroxydeoxyguanosine (8-OHDG) are prognostic of a poor prognosis in patients with hypertensive intracerebral haemorrhage. Methods: The 194 patients in the cerebral haemorrhage group were hospitalised with hypertensive cerebral haemorrhage between January 2022 and January 2024. Forty-five healthy individuals who underwent concurrent physical examinations at the hospital were selected to form the healthy control group. To observe the differences in the levels of serum PAF-AH, VILIP-1 and 8-OHDG, the relationship with the amount of intracerebral haemorrhage, the severity of intracerebral haemorrhage and poor prognosis, and how effectively it predicts the bad outcome of patients suffering from hypertensive intracerebral haemorrhage. Results: Serum PAF-AH, VILIP-1, and 8-OHDG levels were substantially greater in the brain haemorrhage group than in the healthy control group (P