Evaluation of CRP and D-dimer of Confirmed COVID-19 patients at a Tertiary Care Hospital, Correlation with Comorbidity

Since the COVID-19 outbreak started in 2019 in China, several types of research have been done on this disease But the outcome was not always satisfactory. As frequent changes occur in one’s genome, signs and symptoms of this disease vary in different variants. Many investigations have been employed for the detection of COVID-19 infection. Of these, D-dimer and CRP are used to evaluate the presence of systemic response against coronavirus insult. To evaluate whether CRP and D-d-imer levels are significantly higher in COVID-19 patients with respiratory manifestations compared to those with non-respiratory symptoms. 80 male patients were selected randomly, and divided into 2 groups; 40 patients presented with severe respiratory distress symptoms, and 40 presented with symptoms other than respiratory features (mostly gastric symptoms with high fever). CRP and D-dimer tests were done and data were used for subsequent statistical analysis. There was a significant difference in the level of both CRP and D-dimer between patients with dyspnea and those with no respiratory manifestation of COVID-19. In conclusion, a high level of both CRP and D-dimer is a highly suggestive respiratory insult and future complication of COVID-19.