LLM-Assisted Virtual Expert Weight Elicitation in Pharmaceutical Supply Chains: A Z-Number Multi-Agent Framework

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Authors: Jamal Musbah, Ibrahim Badi
Cited by: 4

Abstract

The elicitation of criteria weights in spatial and logistical Multi-Criteria Decision Making (MCDM) typically relies on panels of human domain experts. However, in specialized high-stakes contexts such as pharmaceutical inventory management, expert availability is scarce, expensive, and subject to cognitive biases. This study proposes a novel methodological framework that offers a structured alternative to traditional human panels by employing a Multi-Agent System (MAS) of Large Language Models (LLMs) to generate subjective weights. We introduce a rigorous Z-number-based fuzzy AHP approach in which LLMs, acting as autonomous virtual experts, defined as Agents LLM1, LLM2, and LLM3, perform iterative pairwise comparisons. The methodology strictly separates internal logical consistency, verified via Consistency Ratios (CR) on crisp matrices, from confidence modeling, which is handled via Z-numbers. The LLM-derived weights were aggregated over k=3 iterations to mitigate stochasticity and hybridized with objective CRITIC weights to rank nine Vendor Managed Inventory (VMI) policies. Results indicate strong ranking invariance across all agents and hybridization ratios (ρ=1.0). Beyond numerical stability, the framework demonstrates "behavioral isomorphism" with human ethical standards, explicitly enforcing a "safety-first" constraint. This suggests that LLM-driven frameworks exhibit "dominance stability," positioning them as robust cognitive simulators that align optimization metrics with domain-specific priorities such as patient safety.

Fields of Study & Subjects

Forecasting Techniques and Applications Mobile Crowdsensing and Crowdsourcing Multi-Agent Systems and Negotiation

Publication details

Journal / source
Intelligent Systems Research and Applications Journal
Publisher
Nexora Academic Press
Volume
2
Pages
27–39
Publication date
10 January 2026