HYPoxic Enhancement Before Major Surgery (HYPE): A pilot randomised controlled trial of preoperative Roxadustat vs placebo in patients undergoing major surgery

Australian and New Zealand College of Anaesthetists eBooks 2026 Book Open access

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Authors: Andrew Toner
DOI: 10.60115/11055/1394
Cited by: 0

Abstract

This is a phase 2, single-centre, double-blind, placebo-controlled randomized trial to evaluate the safety and potential eZicacy of preoperative roxadustat in patients undergoing elective major noncardiac surgery. Patients take three preoperative doses of roxadustat 100mg or placebo with dose 1 four days before surgery, dose 2 two days before surgery and dose 3 on the morning of surgery.

Fields of Study & Subjects

Erythropoietin and Anemia Treatment Cardiac Anesthesia and Surgical Outcomes Blood transfusion and management

Publication details

Journal / source
Australian and New Zealand College of Anaesthetists eBooks
Publication date
11 March 2026
Language
EN
Document type
Book