An observational study to compare the treatment outcomes of older and newer antiretroviral regimen in HIV patients
Abstract
The need to compare the effectiveness and adverse effects of Dolutegravir-based regimens versus older TLE regimens in HIV treatment is relevant. Therefore, it is of interest to evaluate their comparative outcomes in a clinical setting including 180 adults with HIV. Results showed comparable efficacy in CD4 counts and viral load between the two groups, although Dolutegravir seemed to cause a quicker increase in CD4 counts. This study contributes to the existing body of knowledge by providing direct comparisons of Dolutegravir-based and older TLE regimens in HIV treatment, highlighting both efficacy and safety outcomes, with a specific focus on CD4 count progression and adverse effects.
Fields of Study & Subjects
HIV/AIDS drug development and treatment
HIV/AIDS Research and Interventions
HIV Research and Treatment
Publication details
- Journal / source
- Bioinformation
- Volume
- 22
- Issue
- 1
- Pages
- 98–101
- Publication date
- 31 January 2026
- Language
- EN