Effect of endotracheal tube cuff pressure on postoperative outcomes in Laparoscopic cholecystectomy

Despite widespread use of nitrous oxide in laparoscopic cholecystectomy, its impact on endotracheal tube cuff pressure, hemodynamics and postoperative complications remains insufficiently characterized. This study compared the effects of air and nitrous oxide as inflating agents on haemodynamic parameters, postoperative complications and endotracheal tube cuff pressure in patients undergoing laparoscopic cholecystectomy. A total of 148 patients were monitored for intraoperative vital signs and cuff pressures at 30, 60 and 90 minutes. Postoperative issues such as dysphagia, hoarseness and sore throat were assessed immediately and 24 hours after surgery. Nitrous oxide significantly increased cuff pressure (p < 0.001) and was associated with a higher incidence of sore throat (25.68% vs. 9.46%, p = 0.007). These findings highlight the importance of careful cuff pressure monitoring to reduce postoperative complications and ensure patient safety.