Effect of diode laser on self-assembling peptide enamel remineralization - In vitro study

The caries lesions of early enamel caries do not have effective non-invasive treatment modalities and thus it is necessary to research on whether the adjunctive diode laser therapy can increase the ability of self-assembled peptide (SAP) biomaterials in remineralization. Eighty premolars had been extracted and randomly separated into four groups (n= 20 each): the control group (artificial saliva), Group B (SAP), Group C (diode laser), and Group D (SAP + diode laser). The process of remineralization lasted 7 days, and the microhardness of surfaces was tested. SAP (P11-4) was very effective on remineralizing the demineralized enamel than the control, whereas diode laser was relatively ineffective. The diode laser used with SAP had synergies with high enamel microhardness recovery. Thus, we show that the use of diode laser can be an effective adjunct in management of early caries through the use of biomimetic remineralizing agents in non- invasive.