Role of endocervical curettage during colposcopy for women with abnormal cervical screening results in predicting cervical intraepithelial neoplasia
Abstract
The problem of accurately predicting high-grade cervical intraepithelial neoplasia (CIN2+) in women with positive screening tests remains a challenge in clinical practice. Therefore, it is of interest to evaluate the role of endocervical curettage (ECC) in predicting high-grade cervical intraepithelial neoplasia (CIN2+) in women with positive screening tests. Conducted at Bangabandhu Sheikh Mujib Medical University, the study included 112 women aged 30-60 with abnormal Pap smears or VIA-positive results. While colposcopy-directed biopsy (CDB) detected 23.2% of CIN2+ cases, ECC in combination with CDB identified 35.7%. Data shows that ECC to enhance detection but with lower sensitivity (38.5%) and positive predictive value (41.7%) compared to biopsy alone. ECC proved beneficial in improving CIN2+ detection in high-risk groups.
Fields of Study & Subjects
Cervical Cancer and HPV Research
Women's cancer prevention and management
Endometrial and Cervical Cancer Treatments
Publication details
- Journal / source
- Bioinformation
- Volume
- 22
- Issue
- 1
- Pages
- 418–424
- Publication date
- 31 January 2026
- Language
- EN