Multifaceted benefits of xylitol in oral health: from caries prevention to periodontal therapy

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Authors: Nidhiswi Yeruva, Luisana Rodriguez, Melania Romero, Anjali Aryal, Leonardo Acosta Pina, Mihriban Sayğı
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Abstract

Xylitol, a naturally occurring sugar alcohol, exhibits multifaceted benefits in dentistry, including inhibition of cariogenic bacteria, suppression of biofilm formation and stimulation of salivary flow. Therefore, it is of interest to review synthesizes current evidence on its role in caries prevention, periodontal therapy and management of xerostomia, candidiasis and halitosis. Clinical and public health implications have been discussed, with emphasis on optimal dosage, delivery methods and integration into preventive strategies. Emerging evidence highlights its relevance as a safe and adjunctive modality within evidence-based preventive and therapeutic protocols. Future studies should include rigorously designed randomized controlled trials and translational studies to establish standardized guidelines for integrating it into clinical practice and community-based oral health programs.

Fields of Study & Subjects

Oral microbiology and periodontitis research Dental Health and Care Utilization Oral Health Pathology and Treatment

Publication details

Journal / source
Bioinformation
Volume
22
Issue
1
Pages
588–592
Publication date
31 January 2026
Language
EN