Dynamic changes in liquid biopsy markers during OSCC treatment: A longitudinal study

Bioinformation 2026 Open access

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Authors: Ajesh Joseph, Gaurav Khatri, Surapaneni Keerthi sai, Tejashwini Kotian, Shoab Nazir, Halima Zakir
DOI: 10.6026/973206300221198
Cited by: 0
References: 1

Abstract

Oral Squamous Cell Carcinoma (OSCC) is often diagnosed at an advanced stage, leading to poor prognosis and limited treatment options. Traditional diagnostic methods are invasive and lack real-time monitoring capabilities. Therefore, it is of interest to investigate the dynamic changes in liquid biopsy markers circulating tumor deoxyribonucleic acid (ctDNA), circulating tumor cells (CTCs), exosomes and micro ribonucleic acids (microRNA) during OSCC treatment. Thus, we show that these markers can effectively monitor treatment response and predict survival outcomes. This research advances the knowledge of liquid biopsies as a non-invasive tool for personalized OSCC management and early relapse detection.

Fields of Study & Subjects

Cancer Genomics and Diagnostics Head and Neck Cancer Studies Extracellular vesicles in disease

Publication details

Journal / source
Bioinformation
Volume
22
Issue
2
Pages
1198–1202
Publication date
28 February 2026
Language
EN