Comparison of intralesional 5-fluorouracil versus intralesional triamcinolone acetonide for keloid treatment: A prospective randomised double-blind controlled study

Bioinformation 2026 Open access

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Authors: Vishwa Deep, Prabhat Shrivastava
DOI: 10.6026/973206300221244
Cited by: 0
References: 1

Abstract

Keloid scars pose significant treatment challenges due to excessive collagen deposition, causing pain, functional impairment and psychological distress despite multiple available interventions. Therefore, it is of interest to compare intralesional 5-fluorouracil (5-FU, 50 mg/mL) versus triamcinolone acetonide (40 mg/mL) in 30 patients randomly assigned to two equal groups. Vancouver Scar Scale parameters (height, pliability, vascularity, pigmentation), pain (Visual Analogue Scale) and pruritus were assessed at treatment end and 2-month follow-up. Both treatments achieved significant VSS improvement (p

Fields of Study & Subjects

Dermatologic Treatments and Research Systemic Sclerosis and Related Diseases Wound Healing and Treatments

Publication details

Journal / source
Bioinformation
Volume
22
Issue
2
Pages
1244–1249
Publication date
28 February 2026
Language
EN