Cariogenic microorganisms induce oral epithelial atypia through host-microbiome-high sugar diet interactions
Abstract
This dataset comprises raw immune marker data and sequencing reads, which are integral to our investigation into oral mucosal development during infancy. The study specifically examines how early-life co-infection with Streptococcus mutans and Candida albicans, particularly when combined with a sucrose-enriched diet, affects oral epithelial homeostasis. The data support observations of atypical hyperplasia and parakeratosis of the tongue, providing crucial insights into how these disruptions might compromise barrier function and heighten susceptibility to oral diseases throughout life.
Fields of Study & Subjects
Oral microbiology and periodontitis research
Oral Health Pathology and Treatment
Gut microbiota and health
Publication details
- Journal / source
- UR Research (University of Rochester)
- Publication date
- 1 January 2026
- Language
- EN
- Document type
- Dataset