Mumford_et_al_2022_Fig3_Western blots

The abundance of FL-APP and CTF is not altered by trisomy of Hsa21. (A-D)The relative abundance of full-length APP (FL-APP), APP β-C-terminal fragment (β-CTF) and APP α-C-terminal fragment (α-CTF) compared to β-actin was measured by western blot using A8717 primary antibody in the cortex at 3-months of age in female and male mice. Uncropped western blots