Dataset for: Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling

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Authors: Stephan Köstlbacher, Jolien van Hooff, Kassiani Panagiotou, Daniel Tamarit, Kathryn E. Appler, Brett J Baker, Valerie De Anda, Thijs J. G. Ettema
Cited by: 1

Abstract

This repository contains the dataset, protein database, predicted structures, and phylogenetic analyses supporting the manuscript: "Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling"The data includes the Asgard archaea protein database, structural model predictions, multiple sequence alignments (MSAs), and IQ-TREE phylogenetic outputs.File Inventory1. Protein Databases & AnnotationsAsgard_DB.faa.gz: The comprehensive Asgard archaea protein database (FASTA amino acid format) used for this study.Asgard_structure_anno.tsv: Functional and structural annotations for the predicted proteins, including confidence scores and domain mappings.2. Structural Modeling Dataall_structures.tar.gz: The complete set of predicted protein structures generated in this study.Asgard_best_structures.zip: A filtered set containing the highest-confidence/best-ranked structural models.Asgard_cluster_summary.tar.gz: Summary statistics and metadata regarding the structural clustering analysis.3. Orthology & AlignmentsAsgard_denovo_ogs.tar.gz: Sequences for the de novo defined Orthologous Groups (OGs).Asgard_denovo_ogs_aln.tar.gz: Multiple Sequence Alignments (MSAs) corresponding to the de novo OGs.Asgard_ascogs.tar.gz: Data related to Asgard-specific Clusters of Orthologous Groups (AsCOGs).4. Phylogeneticsfigshare_phylogenomics.tar.gz: Input data and outputs for the phylogenomic species tree reconstruction (including concatenated alignments).20240619_supplemental_data_phylogenies.tar.gz: Supplemental single-gene phylogenies and associated IQ-TREE output files.

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Document type
Dataset