WRN structural flexibility showcased through fragment-based lead discovery of inhibitors

Figshare 2026 Dataset Open access

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Authors: R.L. Palte, Mihir Mandal, Justyna Sikorska, Artjohn Villafania, Meredith M. Rickard, Robert Bauer, Xiaomei Chai, Jiafang He, Zahid Hussain, Markus Koglin, Hannah E. Bruce Macdonald, My Sam Mansueto
+11 more K. Maskos, Joey L. Methot, Aileen Soriano, Marcel J. Tauchert, Sriram Tyagarajan, Minjia Zhang, Daniel da Silva Klein, Jacqueline D. Hicks, David G. McLaren, Sandra B. Gabelli, Daniel F. Wyss
DOI: 10.6084/m9.figshare.28350992
Cited by: 0

Abstract

pdb coordinates files and mtz files for hWRN protein structures both apo and in complex with ligands

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Document type
Dataset