Extra-corporeal liver cross-circulation using transgenic porcine xenografts with human brain-dead research donors

Figshare 2026 Dataset Open access

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Authors: Abraham A. Shaked, Alexander Sagar, Kim M. Olthoff, Peter L. Abt, Emily Vail, Niels Martin, Charles S. Abrams, Rick D. Hasz, Christine Radolovic, James F. Markmann, Susan Low, Leanne Lanieri
+13 more Kirsten G. Swenson, Gregory T. Everson, David Wagner, Mohammed Elzawahry, John Fallon, Syed Hussain Abbas, Danielle Fortuna, Emma Elizabeth Furth, Rajender Reddy, Peter Philip Reese, Peter John Friend, Mike Curtis, Bao‐Li Loza
DOI: 10.6084/m9.figshare.29318948
Cited by: 0

Abstract

Extracorporeal perfusion of brain-dead decedent with genetically modified porcine liver. Data on bile production, clinical pathology and coagulation parameters, hemodynamic stability of decedent with vitals, histopathology and immunohistochemistry. Results of metabolic assays from HepQuant, LLC. and Metabolic Solutions to determine functionality of porcine liver and/or native liver during and after extracorporeal perfusion.

Fields of Study & Subjects

Xenotransplantation and immune response Organ Transplantation Techniques and Outcomes Tissue Engineering and Regenerative Medicine

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Language
EN
Document type
Dataset