Figure 2A-B primary data

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Authors: Marta Gaglia, Machika Kaku
Cited by: 0

Abstract

Figure 2A-B legend. BC3-IFN-βp-tdTomato reporter cells were treated with 20 ng/mL TPA for 48 hours to induce the lytic cycle (“lytic (+TPA)”). Where indicated, the cells were also treated with 10 μM of the pan-caspase inhibitor IDN-6556 (“casp-i”) and a cocktail of antibodies against type I IFNs and their receptor (“anti-IFN Abs”) at 1:2000 dilution. IFN-β, tdTomato, and ORF50 mRNA levels were measured by RT-qPCR and normalized to 18S rRNA. mRNA levels are plotted relative to the lytic+casp-i sample.

Fields of Study & Subjects

interferon and immune responses Herpesvirus Infections and Treatments NF-κB Signaling Pathways

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Document type
Dataset