Figure 2A-B primary data
Abstract
Figure 2A-B legend. BC3-IFN-βp-tdTomato reporter cells were treated with 20 ng/mL TPA for 48 hours to induce the lytic cycle (“lytic (+TPA)”). Where indicated, the cells were also treated with 10 μM of the pan-caspase inhibitor IDN-6556 (“casp-i”) and a cocktail of antibodies against type I IFNs and their receptor (“anti-IFN Abs”) at 1:2000 dilution. IFN-β, tdTomato, and ORF50 mRNA levels were measured by RT-qPCR and normalized to 18S rRNA. mRNA levels are plotted relative to the lytic+casp-i sample.
Fields of Study & Subjects
interferon and immune responses
Herpesvirus Infections and Treatments
NF-κB Signaling Pathways
Publication details
- Journal / source
- Figshare
- Publication date
- 1 January 2026
- Document type
- Dataset