From Early-Onset Asthma to Chronic Obstructive Pulmonary Disease: Potential Mediating Proteins and Therapeutic Targets

These tables summarize the full results of our proteome-wide Mendelian randomization analyses, encompassing all tested proteins and analytical approaches. Cis‑pQTLs were used to assess the causal effects of circulating proteins on early-onset asthma (EOA) and early-onset asthma–related chronic obstructive pulmonary disease (COPD). Notably, within the MHC region, the highly complex linkage disequilibrium structure may give rise to undetected pleiotropic effects.Detailed methodological information is provided in the referenced article (Jiang Y, Guo J, Wang Y. From Early-Onset Asthma to Chronic Obstructive Pulmonary Disease: Potential Mediating Proteins and Therapeutic Targets. Briefings in Bioinformatics).