Cut Retrosynthesis

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Authors: A. Pirolo
Cited by: 0

Abstract

100% strategic accuracy rate. This work demonstrates that molecular reactivity is an emergent property of topological information flow, offering a deterministic, energy-efficient alternative for industrial-scale drug discovery. Current approaches to computer-aided retrosynthesis rely heavily on data-intensive Deep Learning models, which function as "black boxes" and require massive reaction databases for training.

Publication details

Journal / source
Figshare
Publication date
1 January 2026