Additional file 3 of GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

Additional file 3 (Supplementary Figure 3. GSDMD deficiency, the overexpression of TAU and the treatment with DMF do not produce changes in the number of cells in CA3 area of hippocampus. Quantification of cells in CA3 region of (A) Gsdmd+/+ and Gsdmd-/- mice that overexpress TAUP301L on the ipsilateral side, (B) AAV-TAUP301L mice treated with VEH or DMF and (C) 8-month-old Tg-TAUP301S mice and WT mice treated with VEH or DMF. Bars represent the mean of 4-6 samples ±SEM.)