Supplemental Figures

Figure S1: Representative pictures of H&E staining of male gWAT (left) and male iWAT (right) from Tagln1-Cre Ercc1 mice showing thickened vascular wall of the microvasculature.Figure S2: Ercc1 mRNA expression in different tissues from 8- and 22-week-old Tagln1-Cre Ercc1 mice compared to WT mice.Figure S3: Western blot following acute insulin test in male mice analyzing total AKT and phosphorylated AKT protein expression in gonadal, axillary, and inguinal WAT (gWAT, aWAT, iWAT respectively) and brown adipose tissue depots (BAT). Analyzed in a 2-way ANOVA with *: significant effect of the genotype and $: significant effect of injection with insulin with p