Additional file 1 of Circulating microRNA signatures for echinococcosis

Additional file 1. Fig. S1 Analysis of the isolated hepatocytes by RT-qPCR. Additional file 1. Fig. S2 Comparative analysis of the basal levels of differentially expressed abmiRNAs in the hepatocytes of infected mice. Additional file 1. Fig. S3 Analysis of the relative expression levels of abmiRNAs in the organs/tissues of healthy mice. Additional file 1. Table S1 The primers used in this study. Additional file 1. Table S2 Argonaute 2-binding miRNAs (abmiRNAs) in the hepatocytes of mice with or without Echinococcus multilocularis infection. Additional file 1. Table S3 Differentially expressed abmiRNAs in response to Echinococcus multilocularis infection. Additional file 1. Table S4 Analysis of the sensitivity of circulating miRNA-targeted qPCR using recombinant plasmids. Additional file 1. Additional file 1. Table S5 Youden’s index analysis of miR-192-5p-targeted qPCR. Additional file 1. Table S6 Youden’s index analysis of miR-122-5p-targeted qPCR. Additional file 1. Table S7 Youden’s index analysis of miR-21a-5p-targeted qPCR. Additional file 1. Table S8 Comparison of the established qPCR approaches targeting individual circulating miRNAs molecules and their combinations in discriminating E. multilocularis-infected mice from healthy mice.