The gsmap results of sick sinus syndrome and atrial fibrillation

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Authors: Zhaoqi Yan
Cited by: 0

Abstract

This folder contains gsMap output for the traits Atrial Fibrillation and Sick Sinus Syndrome on the MOSTA E16.5_E1S1 spatial transcriptomics sample. For each trait, there are three visualization subfolders: gsMap_plot/ (spatial maps showing where the trait-associated signal is enriched across the tissue section), GSS_plot/ (plots of Gene Specificity Score, GSS, illustrating where candidate genes are specifically expressed in space), and manhattan_plot/ (GWAS-style Manhattan/diagnostic plots summarizing genomic association signals). In addition, E16.5_E1S1.MOSTA_*_Gene_Diagnostic_Info.csv provides a gene-level diagnostic table (e.g., genes with their spatial annotation, summary GSS metrics such as median GSS, and correlation-style indicators linking spatial specificity to GWAS signal), while E16.5_E1S1.MOSTA_*_gsMap_Report.html is an integrated HTML report that brings together the key figures and summaries for quick interpretation and result review.

Fields of Study & Subjects

Cardiac electrophysiology and arrhythmias Single-cell and spatial transcriptomics Genetic Associations and Epidemiology

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Document type
Dataset