Additional file 2 of Evolutionary trajectories and zoonotic potential of a PB2 mutation triad (I147T, K339T, and A588T) in avian influenza viruses

Additional file 2. The emergence of mutations in avian, swine, and human hosts. Mutation frequency and number of PB2 sequences in avian (wild bird and poultry, blue), swine (red), and human (green) viruses harboring MVV-I147T (A), MVV-K339T (B), and MVV-A588T (C). The sequence names depicted in bold letters indicate the first isolated virus in each host. All the analyzed sequences were collected from the GISAID database on 2023.09.12, and human H1 and H3 subtypes were excluded from the analysis.