High-Altitude Exercise Performance and Acute Mountain Sickness Unchanged Following Cold Water Habituation Supplemental Tables S1-S8

This study sought to determine if cold-hypoxia CA, induced by repeat cold water immersion (CWI) and compared to a thermoneutral water (TN) control, could reduce resting and submaximal exercise physiologic strain, improve exercise performance, and decrease the incidence and severity of acute mountain sickness (AMS) symptoms during a 29-h exposure to hypobaric hypoxia (~4100m). Supplemental Tables S1-S3: To address data not missing at random, all linear mixed models were run secondarily as repeated measures ANOVAs with listwise deletion. All post hoc comparisons were made using a Bonferroni correction. All data are presented as mean ± SD.Supplemental Tables S4-S8: Main and interaction (order x temperature) sequence effects were investigated using linear mixed models with random intercept for participant to explore the potential long-term (>2 week) physiological influence of repeated cold water immersions. All post hoc comparisons were made using a Bonferroni correction. Data is presented as mean difference [95% CI] between Cold and TN.