Additional file 1 of Adaptive-like CAR-iPSC-CD4⁺ T cells outperform CD8⁺ counterparts in sustained ALL control

Supplementary Material 1: Figure S1. Differentiation of various iPSC lines into T cells using the artificial thymic organoid (ATO) system. Figure S2. Phenotypic analysis of iPSC-derived CD4⁺ and CD8⁺ T cells before and after initial expansion. Figure S3. Activation phenotype of iCD4⁺ and iCD8⁺ T cells. Figure S4. Cytokine production capacity of iCD4⁺ and iCD8⁺ T cells. Figure S5. Functional characterization of αβ CD4⁺ T cells derived from non-T iPSC line FFI01s04 (FF-iCD4.+ T Cells). Figure S6. Functional enrichment analysis of differentially expressed genes between ATO-derived ESC-CD4⁺ and ESC-CD8⁺ T cells. Figure S7. Cytokine production by iPSC-derived CD4⁺ and CD8⁺ T cells during serial stimulation.