In situ Perturb-seq applied to A375 melanoma tumors

Figshare 2026 Dataset Open access

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Authors: Livnat Jerby
DOI: 10.6084/m9.figshare.31119634
Cited by: 1

Abstract

In situ Perturb-seq is a method for pooled optical genetic screens with spatial transcriptomics readouts in the intact tissue. Here in situ Perturb-seq was applied to A375 melanoma tumors in NSG mice to investigate top T cell receptor (TCR)-specific immunomodulating hits identified in the melanoma CRISPR activation screens.

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Document type
Dataset