Algorithm to increase the maximum count rate of nanoparticles measured by flow cytometry
Abstract
A pulse fitting algorithm was developed and validated to extend the operating range of flow cytometry at high particle concentrations. Tested on polystyrene beads and Intralipid samples, the algorithm enabled accurate quantification up to 3.0E+5 to 4.6E+5 events per second, representing a 10- to 49-fold improvement over conventional electronics.
Fields of Study & Subjects
Microfluidic and Bio-sensing Technologies
Advanced Measurement and Detection Methods
Advanced Fluorescence Microscopy Techniques
Publication details
- Journal / source
- Figshare
- Publication date
- 29 January 2026
- Document type
- Dataset