Additional file 1 of Association between nafamostat mesylate infusion dose and dialysis circuit occlusion in continuous renal replacement therapy: a retrospective cohort study

Additional file 1. Title of data: Directed acyclic graph showing the assumed causal network between NM administration and extracorporeal circuit occlusion. Description of data: Pink nodes indicate potential confounders that may influence both NM use and circuit occlusion, including filter type, oral antithrombotic drug, BMI, SOFA score, bleeding risk, and sepsis. Blue nodes represent the prognostic factors hypothesized to affect circuit occlusion only, including diabetes mellitus, HD, Lac, and CRP. NM, nafamostat mesylate; BMI, bodymass index; SOFA, Sequential Organ Failure Assessment; HD, hemodialysis vintage; Lac, serum lactate; CRP, Creactive protein.