ACOT8-mediated palmitate accumulation promotes M1 macrophage polarization in renal ischemia–reperfusion injury via activation of the cGAS–STING pathway

Figshare 2026 Dataset Open access

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Authors: Haoxun Zhang
DOI: 10.6084/m9.figshare.31167790
Cited by: 0

Abstract

The precise etiology, intrinsic mechanisms, and effective interventions of renal ischemia-reperfusion injury are not sufficiently understood.To investigate the molecular basis, we carried out single-cell RNA sequencing using two distinct mouse models: Sham and IRI.

Fields of Study & Subjects

Acute Kidney Injury Research Immune cells in cancer Autophagy in Disease and Therapy

Publication details

Journal / source
Figshare
Publication date
11 March 2026
Language
EN
Document type
Dataset