Additional file 7 of Advancing prion diagnostics: full-length human E200K RT-QuIC substrate facilitates prion detection in tear fluid and improves sensitivity in cerebrospinal fluid

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Authors: Susana Correia, Matthias Schmitz, Péter Hermann, Stefan Goebel, Jaqueline Gerecke, Paul Lingor, Fabian Maass, Anna-Lisa Fischer, Sezgi Canaslan, Hasier Eraña, Joaquín Castilla, Angela da Silva Correia
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Abstract

Supplementary Figure 7: RT-QuIC seeding kinetics of a false positive AD-patient. The RT-QuIC was seeded with TF from a non-prion control. Two out of three reactions were considered as positive. The clinical assessment supports a diagnosis of mild to moderate Alzheimer’s dementia

Fields of Study & Subjects

Prion Diseases and Protein Misfolding Amyloidosis: Diagnosis Treatment Outcomes Alzheimer's disease research and treatments

Publication details

Journal / source
Figshare
Publication date
1 January 2026