Additional file 1 of Post-Covid-19 symptoms, subjective work ability and sick leave 2 years after acute infection—results from a population-based long COVID study

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Authors: Stefanie Braig, Raphael S. Peter, Alexandra Nieters, Hans-Georg Kräusslich, Stefan Brockmann, Siri Göpel, Uta Merle, Jürgen Michael Steinacker, Winfried V. Kern, Dietrich Rothenbacher
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Abstract

Additional file 1. Supplementary Figure 1: Prevalence of regained work ability at 6-12 and 24 months after initial infection (mWAI1, categorized) and mean weeks of sick leave according to age, working task, and comorbid mental disorders. The lighter shades symbolize 6-12 months the darker shades 24 months. 6-12M: 6-12 months, 24M: 24 months, mWAI1: regained modified work ability. Supplementary Figure 2: Trajectories of work ability (mWAI1, categorized) in n=5422 participants, 6-12 months and 24 months after infection according to age, working task, and comorbid mental disorders. 6-12M: 6-12 months, 24M: 24 months, mWAI1: regained modified work ability. Supplementary Figure 3: Trajectories of work ability (mWAI1, categorized) 6-12 months and 24 months after infection according to symptom clusters newly occurred 6-12 months after initial infection. 6-12M: 6-12 months, 24M: 24 months, mWAI1: regained modified work ability. Supplementary Figure 4: Co-occurrence of the three most prevalent symptom clusters 24 months after infection according to sick leave (24 months after infection). Numbers in the graphs are %. Supplementary Table 1: Prevalence of the six most common symptom clusters at 6-12 months and at 24 months and mean time of sick leave (weeks). Supplementary Table 2: Association between potential risk factors including symptom clusters measured 24 months after initial infection and task related work ability (mWAI2 measured at 24 months). Results of a mutually adjusted linear regression analysis (n=5422). Supplementary Table 3A: Association between potential risk factors including symptom clusters measured 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by age. Supplementary Table 3B: Association between potential risk factors including symptom clusters measured 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by age among female participants. Supplementary Table 3C: Association between potential risk factors including symptom clusters measured 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by age among male participants. Supplementary Table 3D: Association between potential risk factors including symptom clusters measured 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by working task. Supplementary Table 3E: Association between potential risk factors including symptom clusters measured 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by working task among female participants. Supplementary Table 3F: Association between potential risk factors including symptom clusters measured 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by working task among male participants. Supplementary Table 3G: Association between potential risk factors including symptom clusters reported 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by comorbid mental disorders. Supplementary Table 3H: Association between potential risk factors including symptom clusters reported 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by comorbid mental disorders among female participants. Supplementary Table 3I: Association between potential risk factors including symptom clusters reported 24 months after initial infection and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis stratified by comorbid mental disorders among male participants. Additional file 1, Supplementary Table 4: Association between potential risk factors including symptom clusters reported 24 months after initial infection and weeks of sick leave. Results of a mutually adjusted linear regression analysis (n = 5422). Supplementary Table 5: Association between potential risk factors including post-exertional malaise or ME/CFS and task related work ability (mWAI2). Results of a mutually adjusted linear regression analysis (n = 5422). Supplementary Table 2: mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3A: mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3B: mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05.Supplementary Table 3C:mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3D:mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3E: mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3F:mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3G: mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3H: mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 3I: mWAI2: modified work ability index, task related work ability, Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 4: Symptom clusters were not present before the SARS-CoV-2 infection, bold letters indicate statistically significant at p < 0.05. Supplementary Table 5: mWAI2: modified work ability index, task related work ability, bold letters indicate statistically significant at p < 0.05, ME/CFS: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, #in the model with post-exertional malaise we did not adjust for ME/CFS and vice versa.

Fields of Study & Subjects

Long-Term Effects of COVID-19 Medical Practices and Rehabilitation COVID-19 and Mental Health

Publication details

Journal / source
Figshare
Publication date
1 January 2026