Proteomic changes in LNCaP and LNCaP-AKR1C3 cells
Abstract
Radioresistance is one of the primary causes of prostate cancer treatment failure and post-radiotherapy progression. However, there is currently a lack of effective targets to increase radiotherapy sensitivity and inhibit malignant progression. We identified AKR1C3 as a potential key target associated with radioresistance and malignant progression. Here we explore the Proteomic changes in LNCaP and LNCaP-AKR1C3 cells.
Fields of Study & Subjects
Prostate Cancer Treatment and Research
Effects of Radiation Exposure
Aldose Reductase and Taurine
Publication details
- Journal / source
- Figshare
- Publication date
- 1 January 2026
- Document type
- Dataset