Additional file 5 of LDOC1 connects histone H2B monoubiquitination to tumor cell plasticity in non-small cell lung cancer

Figshare 2026 Open access

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Authors: Hsien‐Neng Huang, Pin-Feng Hung, Yi-Ta Tsai, En-Ting Liu, Tai‐Lung Cha, Ya-Pin Chen, Wen‐Tsan Weng, Chiao-Yin Sun, Wei-Hsuan Yu, Hau-Lun Cheng, Chia‐Huei Lee
DOI: 10.6084/m9.figshare.31199430
Cited by: 0

Abstract

Supplementary Material 5: Validation of LDOC1-dependent chromatin accessibility changes using an independent shRNA in A549 cells. (a) Heatmaps of ATAC-seq signal intensity (±3 kb around peak summits) for unchanged peaks, shLDOC1-2–repressed peaks, and shLDOC1-2–induced peaks in A549-shCtrl-2 versus A549-shLDOC1-2 cells. (b) Genomic distribution of ATAC-seq peaks in each category (unchanged, shLDOC1-2–repressed, shLDOC1-2–induced), annotated according to gene-associated features.

Fields of Study & Subjects

Genomics and Chromatin Dynamics Epigenetics and DNA Methylation Chromatin Remodeling and Cancer

Publication details

Journal / source
Figshare
Publication date
1 January 2026