Additional file 8 of LDOC1 connects histone H2B monoubiquitination to tumor cell plasticity in non-small cell lung cancer

Figshare 2026 Open access

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Authors: Hsien‐Neng Huang, Pin-Feng Hung, Yi-Ta Tsai, En-Ting Liu, Tai‐Lung Cha, Ya-Pin Chen, Wen‐Tsan Weng, Chiao-Yin Sun, Wei-Hsuan Yu, Hau-Lun Cheng, Chia‐Huei Lee
DOI: 10.6084/m9.figshare.31199439
Cited by: 0

Abstract

Supplementary Material 8: Altered transcriptome caused by LDOC1 knockdown in A549 cells. MetaCore pathway enrichment analysis of upregulated (a) and downregulated (b) pathways in A549-shLDOC1 cells based on transcriptomic profiling. Metastasis-related pathways are marked with red stars. (c, d) Heatmaps showing significantly upregulated (c) and downregulated (d) metastasis-related genes in A549-shLDOC1 cells. Fold-change (FC) values were calculated from Affymetrix microarray data; genes with FC > 2 or < –2 and p < 0.05 were considered significant.

Fields of Study & Subjects

Cancer Cells and Metastasis Epigenetics and DNA Methylation Genomics and Chromatin Dynamics

Publication details

Journal / source
Figshare
Publication date
1 January 2026