4D-DIA-based proteomics analysis reveals changes in expression during palatal development.
Abstract
Palatal mesenchymal cells play important roles in the formation of palate. A proteomics approach was employed combined with bioinformatics analysis to profile protein changes in mouse embryonic palatal mesenchyme (MEPM) cells during palate development (E13.5-16.5), aiming to elucidate molecular mechanisms. Protein changes were revealed by four-dimensional independent data acquisition (4D-DIA) proteomics.
Fields of Study & Subjects
Cleft Lip and Palate Research
Advanced Proteomics Techniques and Applications
Developmental Biology and Gene Regulation
Publication details
- Journal / source
- Figshare
- Publication date
- 1 January 2026
- Document type
- Dataset