FireGate Biotech FG-002: In Silico Systems Analysis Supporting
Abstract
We performed an in silico systems-level functional association and enrichment analysis usingthe STRING database to assess whether a curated FG-002 viral sensing, interferon signaling, and antigen presentation gene/protein set forms a coherent non-random immune network. The analysis demonstrates dense protein–protein interaction connectivity and strong overrepresentation of viral response, interferon-associated innate immune programs, and antigen processing/presentation pathways. These results support a mechanistic framework in which induction of viral-mimicry-like signaling may promote tumor immunogenicity and immune engagement.
Fields of Study & Subjects
interferon and immune responses
Cancer Immunotherapy and Biomarkers
Immunotherapy and Immune Responses
Publication details
- Journal / source
- Figshare
- Publication date
- 1 January 2026