Comparison of PCR-Based High-Resolution Melting Curve Analysis and Immunohistochemistry in Detecting Microsatellite Instability in Colorectal Cancer: A Consistency Study
Abstract
PCR-HRM is a high-precision, low-cost and efficient MSI screening method. It does not require the PCR post-processing required by the traditional method, thus simplifying the workflow. In addition, it also avoids potential problems related to IHC results. Our research shows that PCR-HRM can be a powerful tool to guide the decision-making of colorectal cancer treatment.
Fields of Study & Subjects
Genetic factors in colorectal cancer
Colorectal Cancer Treatments and Studies
Colorectal Cancer Surgical Treatments
Publication details
- Journal / source
- Figshare
- Publication date
- 1 January 2026
- Document type
- Dataset