Additional file 1 of Elevated plasma glucose links intrafollicular bile acids to altered embryological outcomes in IVF patients

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Authors: Natascha Berger, Giovanny Rodriguez-Blanco, Katharina Brugger, Bettina Amtmann, Neli Hofer, Martina Kollmann, Irmgard Oreskovic, Katharina Eberhard, Samuele Suraci, Slave Trajanoski, Herrmann, Markus, Ursula Hiden
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Abstract

Supplementary Material 1. Figure S1. Correlation matrix of BA species and the sum of UDC species (Total UDCA) between serum and FF. Figure S2. Individual BA profiles in matched serum and FF samples. Figure S3. Evaluation of potential confounding factors influencing group allocation. Figure S4. Presentation of IVF outcome parameters stratified by group. Table S1. Group 2 exhibits significantly higher intrafollicular BA concentrations compared to group 1. Table S2. Regression coefficients for the dependent variable TBA (log-normalized). Table S3. Distribution of clinical diagnosis per group. Table S4. Association between infertility diagnosis and cluster generation, evaluated using Pearson’s chi-square test. Table S5. Comparison of metabolic and IVF parameters between GnRH agonist and antagonist protocols within Groups 1 and 2. Differences were evaluated using Student’s t-test.

Fields of Study & Subjects

Reproductive Biology and Fertility Reproductive Health and Technologies Ovarian function and disorders

Publication details

Journal / source
Figshare
Publication date
1 January 2026