Additional file 6 of Calcineurin depletion coincides with phosphorylated TDP-43 deposition in a mouse model of ALS/FTLD-TDP

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Authors: Sarah M. Waldherr, Randall J. Eck, Joshua C. Hincks, Heather N. Currey, Matvey Goldberg, Pamela J. McMillan, Aleen D. Saxton, Heino Hulsey-Vincent, Caitlin S. Latimer, Brian C. Kraemer, Nicole F. Liachko
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Abstract

Supplementary Material 6. Figure S6: Primary neuron controls and full immunoblots. a–c Mouse primary neurons without exposure to EA have very low or no apparent phosphorylated TDP-43. Arrowhead is at approximate location of full-length TDP-43. d Representative immunostaining of primary neurons for MAPT (red), and DAPI (blue). Scale bar: 25 µm. e–h Full immunoblots for quadruplicate immunoblot experiments presented in Fig. 4. Arrowhead is at approximate location of full-length TDP-43.

Fields of Study & Subjects

Amyotrophic Lateral Sclerosis Research Alzheimer's disease research and treatments Muscle Physiology and Disorders

Publication details

Journal / source
Figshare
Publication date
1 January 2026